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Merck
CN

SAB5701989

Anti-CTBP2 Antibody, clone 1R1U6, Rabbit Monoclonal

Synonym(s):

CTBP2, C-terminal-binding protein 2

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About This Item

NACRES:
NA.46
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
1R1U6, monoclonal
Application:
IF, IHC, IP, WB
Citations:
-
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biological source

rabbit

conjugate

unconjugated

material

colorless

clone

1R1U6, monoclonal

form

liquid

mol wt

47 kDa

concentration

0.33 mg/mL

technique(s)

immunofluorescence: 1:50 - 1:200, immunohistochemistry: 1:50 - 1:200, immunoprecipitation (IP): 1:50 - 1:200, western blot: 1:500 - 1:2000

color

colorless

isotype

IgG

immunogen sequence

TGRIPESLRNCVNKEFFVTSAPWSVIDQQAIHPELNGATYRYPPGIVGVAPGGLPAAMEGIIPGGIPVTHNLPTVAHPSQAPSPNQPTKHGDNREHPNEQ

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

Gene Information

human ... CTBP2(1488)

species reactivity

human

General description

This gene produces alternative transcripts encoding two distinct proteins. One protein is a transcriptional repressor, while the other isoform is a major component of specialized synapses known as synaptic ribbons. Both proteins contain a NAD+ binding domain similar to NAD+-dependent 2-hydroxyacid dehydrogenases. A portion of the 3′ untranslated region was used to map this gene to chromosome 21q21.3; however, it was noted that similar loci elsewhere in the genome are likely. Blast analysis shows that this gene is present on chromosome 10. Several transcript variants encoding two different isoforms have been found for this gene.

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 346-445 of human CTBP2 (P56545).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

WB, IHC, IF/ICC, IP

Storage Class

10 - Combustible liquids

wgk

WGK 1

Regulatory Information

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