SAB5702075
Anti-TAK1 Antibody, clone 1W2B10, Rabbit Monoclonal
Synonym(s):
CSCF,FMD2,MEKK7,TAK1,TGF1a,MAP3K7
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About This Item
NACRES:
NA.46
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
1W2B10, monoclonal
Application:
IP, WB
Citations:
-
biological source
rabbit
conjugate
unconjugated
material
colorless
clone
1W2B10, monoclonal
form
liquid
mol wt
75 kDa
Quality Level
Gene Information
human ... MAP3K7(6885)
concentration
0.16 mg/mL
technique(s)
immunoprecipitation (IP): 1:50 - 1:200, western blot: 1:500 - 1:2000
color
colorless
isotype
IgG
immunogen sequence
LQPLAPCPNSKESMAVFEQHCKMAQEYMKVQTEIALLLQRKQELVAELDQDEKDQQNTSRLVQEHKKLLDENKSLSTYYQQCKKQLEVIRSQQQKRQGTS
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
General description
The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 507-606 of human TAK1 (O43318).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Application
WB, IP
Storage Class
10 - Combustible liquids
wgk
WGK 1
Regulatory Information
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