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Merck
CN

SAB5702300

Sigma-Aldrich

Anti-p73 Antibody, clone 7L1V7, Rabbit Monoclonal

Synonym(s):

TP73, P73, tumor protein p73

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.46

Key Documents

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biological source

rabbit

Quality Level

100

conjugate

unconjugated

material

colorless

clone

7L1V7, monoclonal

form

liquid

mol wt

70 kDa

species reactivity

rat, human, rat

concentration

1.20 mg/mL

technique(s)

immunohistochemistry: 1:50 - 1:200
western blot: 1:500 - 1:2000

color

colorless

isotype

IgG

immunogen sequence

MAQSTATSPDGGTTFEHLWSSLEPDSTYFDLPQSSRGNNEVVGGTDSSMDVFHLEGMTTSVMAQFNLLSSTMDQMSSRAASASPYTPEHAASVPTHSPYA

UniProt accession no.

O15350

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... p73(7161)

General description

This gene encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Many transcript variants resulting from alternative splicing and/or use of alternate promoters have been found for this gene, but the biological validity and the full-length nature of some variants have not been determined.

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human p73 (O15350).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

WB, IHC

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Regulatory Information

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