SAB5702643
Anti-PDZK1 Antibody, clone 5C1D3, Rabbit Monoclonal
Synonym(s):
CAP70, CLAMP, NHERF-3, NHERF3, PDZD1
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About This Item
NACRES:
NA.46
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
5C1D3, monoclonal
Application:
IF, WB
Citations:
-
biological source
rabbit
conjugate
unconjugated
material
colorless
clone
5C1D3, monoclonal
form
liquid
mol wt
70 kDa
concentration
0.49 mg/mL
technique(s)
immunofluorescence: 1:50 - 1:200, western blot: 1:500 - 1:2000
color
colorless
isotype
IgG
immunogen sequence
EDVIIEVNGVNVLDEPYEKVVDRIQSSGKNVTLLVCGKKAYDYFQAKKIPIVSSLADPLDTPPDSKEGIVVESNHDSHMAKERAHSTASHSSSNSEDTEM
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... PDZK1(5174)
species reactivity
human
General description
This gene encodes a PDZ domain-containing scaffolding protein. PDZ domain-containing molecules bind to and mediate the subcellular localization of target proteins. The encoded protein mediates the localization of cell surface proteins and plays a critical role in cholesterol metabolism by regulating the HDL receptor, scavenger receptor class B type 1. Single nucleotide polymorphisms in this gene may be associated with metabolic syndrome, and overexpression of this gene may play a role in drug resistance of multiple myeloma. Pseudogenes of this gene are located on the long arm of chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 420-519 of human PDZK1 (Q5T2W1).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Application
WB, IF/ICC
Storage Class
10 - Combustible liquids
wgk
WGK 1
Regulatory Information
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