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Merck
CN

SAB6010012

Sigma-Aldrich

Anti-acetyl-Histone H4 (K16) antibody, clone 2B8, Rabbit Monoclonal

recombinant, expressed in HEK293F cells

Synonym(s):

Histone H4, HIST1H4A, H4/A, H4FA, AND, HIST1H4B, H4/I, H4FI, AND, HIST1H4C, H4/G, H4FG, AND, HIST1H4D, H4/B, H4FB, AND, HIST1H4E, H4/J, H4FJ, AND, HIST1H4F, H4/C, H4FC, AND, HIST1H4H, H4/H, H4FH, AND, HIST1H4I, H4/M, H4FM, AND, HIST1H4J, H4/E, H4FE, AND, HIST1H4K, H4/D, H4FD, AND, HIST1H4L, H4/K, H4FK, AND, HIST2H4A, H4/N, H4F2, H4FN, HIST2H4, AND, HIST2H4B, H4/O, H4FO, AND, HIST4H4

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About This Item

UNSPSC Code:
12352203

Key Documents

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recombinant

expressed in HEK 293 F cells

Quality Level

100

conjugate

unconjugated

antibody product type

primary antibodies

clone

2B8, recombinant monoclonal

form

liquid

mol wt

150 kDa

purified by

affinity chromatography

species reactivity

mouse, human

concentration

1mg/ml

technique(s)

ELISA: 2000:10000
flow cytometry: 1:50-1:200
immunofluorescence: 1:50-1:200
immunohistochemistry: 1:50-1:200

isotype

IgG

UniProt accession no.

P62805

shipped in

wet ice

storage temp.

-10 to -25°C

target post-translational modification

acetylation (Lys16)

General description

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Immunogen

A synthesized peptide derived from human Acetyl-Histone H4 (K16)

Physical form

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Preparation Note

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Other Notes

GA-(acetyl)K-RH

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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