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Merck
CN

SAB6010032

Sigma-Aldrich

Anti-Histone H4 antibody, clone 21E8, Rabbit Monoclonal

recombinant, expressed in HEK293F cells

Synonym(s):

Histone H4, HIST1H4A, H4/A, H4FA, AND, HIST1H4B, H4/I, H4FI, AND, HIST1H4C, H4/G, H4FG, AND, HIST1H4D, H4/B, H4FB, AND, HIST1H4E, H4/J, H4FJ, AND, HIST1H4F, H4/C, H4FC, AND, HIST1H4H, H4/H, H4FH, AND, HIST1H4I, H4/M, H4FM, AND, HIST1H4J, H4/E, H4FE, AND, HIST1H4K, H4/D, H4FD, AND, HIST1H4L, H4/K, H4FK, AND, HIST2H4A, H4/N, H4F2, H4FN, HIST2H4, AND, HIST2H4B, H4/O, H4FO, AND, HIST4H4

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About This Item

UNSPSC Code:
12352203
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recombinant

expressed in HEK 293 F cells

Quality Level

conjugate

unconjugated

antibody product type

primary antibodies

clone

21E8, recombinant monoclonal

form

liquid

mol wt

150 kDa

purified by

affinity chromatography

species reactivity

human

concentration

1.5mg/ml

technique(s)

ELISA: 2000:10000
flow cytometry: 1:50-1:200
immunofluorescence: 1:50-1:200
immunohistochemistry: 1:50-1:200

isotype

IgG

UniProt accession no.

shipped in

wet ice

storage temp.

-10 to -25°C

target post-translational modification

unmodified

General description

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Immunogen

A synthesized peptide derived from human Histone H4

Physical form

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Preparation Note

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Other Notes

72-103aa

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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