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SAB6010047

Anti-phospho-PPP2CA (Y307) antibody, clone 3F11, Rabbit Monoclonal

recombinant, expressed in HEK293F cells

Synonym(s):

Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, PP2A-alpha, Replication protein C, RP-C, PPP2CA

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
Conjugate:
unconjugated
Clone:
3F11, recombinant monoclonal
Application:
ELISA, FACS, IF, IHC
Citations:
-

Key Documents

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recombinant

expressed in HEK 293 F cells

conjugate

unconjugated

antibody product type

primary antibodies

clone

3F11, recombinant monoclonal

form

liquid

mol wt

150 kDa

purified by

affinity chromatography

species reactivity

human

concentration

0.5mg/ml

technique(s)

ELISA: 2000:10000, flow cytometry: 1:50-1:200, immunofluorescence: 1:50-1:200, immunohistochemistry: 1:50-1:200

isotype

IgG

UniProt accession no.

P67775

shipped in

wet ice

storage temp.

-10 to -25°C

Quality Level

100

target post-translational modification

phosphorylation (pTyr307)

General description

PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGO2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I (By similarity). Can dephosphorylate SV40 large T antigen and p53/TP53. Activates RAF1 by dephosphorylating it at ′Ser-259′.

Immunogen

A synthesized peptide derived from human Phospho-PPP2CA (Y307)

Physical form

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Preparation Note

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Other Notes

PD-pY-FL

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Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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