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SAB6010091

Anti-phospho-MAPT (S324) antibody, clone 4E8, Rabbit Monoclonal

recombinant, expressed in HEK293F cells

Synonym(s):

Microtubule-associated protein tau, Neurofibrillary tangle protein, Paired helical filament-tau, PHF-tau, MAPT, MAPTL, MTBT1, TAU

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
Conjugate:
unconjugated
Clone:
4E8, recombinant monoclonal
Application:
ELISA, FACS, IF, IHC
Citations:
-

Key Documents

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recombinant

expressed in HEK 293 F cells

conjugate

unconjugated

antibody product type

primary antibodies

clone

4E8, recombinant monoclonal

form

liquid

mol wt

150 kDa

purified by

affinity chromatography

species reactivity

human

concentration

0.525mg/ml

technique(s)

ELISA: 2000:10000, flow cytometry: 1:50-1:200, immunofluorescence: 1:50-1:200, immunohistochemistry: 1:50-1:200

isotype

IgG

UniProt accession no.

P10636

shipped in

wet ice

storage temp.

-10 to -25°C

target post-translational modification

phosphorylation (pSer324)

Quality Level

100

General description

Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.

Immunogen

A synthesized peptide derived from human Phospho-MAPT (S324)

Physical form

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Preparation Note

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Other Notes

KG-pS-LK

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Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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