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SAB6012473

KD-Validated Anti BAG cochaperone 3 Antibody, clone 23GB1520, Rabbit Monoclonal

greener alternative

clone 23GB1520, recombinant rabbit monoclonal, expressed in HEK293 cells

Synonym(s):

BAG-3, BIS, CAIR-1, MFM6

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About This Item

UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
23GB1520, recombinant monoclonal
Application:
flow cytometry
immunofluorescence
western blot
Species reactivity:
human
Citations:
Technique(s):
flow cytometry: 1:2000
immunofluorescence: 1:100-:1000
western blot: 1:1,000-1:5,000
Uniprot accession no.:
O95817

Key Documents

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Product Name

KD-Validated Anti BAG cochaperone 3 Antibody, clone 23GB1520, Rabbit Monoclonal, clone 23GB1520, recombinant rabbit monoclonal, expressed in HEK293 cells

biological source

rabbit (Monoclonal)

recombinant

expressed in HEK 293 cells

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

23GB1520, recombinant monoclonal

form

buffered aqueous glycerol solution

mol wt

62 kDa

species reactivity

human

packaging

vial of 1.5 mL

enhanced validation

recombinant expression
Learn more about Antibody Enhanced Validation

Quality Level

100

Gene Information

human ... BAG3(9531)

sustainability

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concentration

0.25 mg/ml

technique(s)

flow cytometry: 1:2000
immunofluorescence: 1:100-:1000
western blot: 1:1,000-1:5,000

isotype

IgG

Ensembl | human accession no.

ENSG00000151929

NCBI accession no.

NP_004272.2

UniProt accession no.

O95817

greener alternative category

DfS-Developed

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Related Categories

General description

BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq, Jul 2008]
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Immunogen

A synthesized peptide corresponding to a sequence within amino acids 60-130 of human Bag3 [NP_004272.2].

Other Notes

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.

Physical form

Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.

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