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Merck
CN

SAB6100009

Anti-IL-6 / IFNb2 Reference Antibody

Synonym(s):

B-cell stimulatory factor-2, BSF-2, interferon beta-2

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About This Item

NACRES:
NA.41
Conjugate:
unconjugated
Clone:
recombinant monoclonal
Application:
ELISA
Citations:
-

Key Documents

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recombinant

expressed in CHO cells

conjugate

unconjugated

antibody product type

primary antibodies

clone

recombinant monoclonal

form

lyophilized

species reactivity

human

concentration

1 mg/mL

technique(s)

ELISA: 0.001-10 μg/mL

optimum pH

6.2

pH range

5.5-6.13

immunogen sequence

MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYILDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLLEFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQAQNQWLQDMTTHLILRSFKEFLQSSLRALRQM

Protein ID accession no.

NP_000591

UniProt accession no.

P05231

storage temp.

-65 to -96°C

target post-translational modification

unmodified, unmodified

Quality Level

100

Gene Information

human ... IL6(3569)

General description

Anti-IL-6 / IFNb2 Reference Antibody, expressed from CHO cells with a heavy chain type of huIgG1 and a light chain type of hukappa, has a predicted MW of 145.5 kDa. This antibody serves as a versatile tool for various research applications. It enables ELISA assays for quantifying IL-6 and IFNb2 expression levels, FACS for precise cell sorting, kinetic studies to analyze its binding properties, functional assays to assess its biological activity, and utilization in animal models to evaluate its efficacy and safety profiles in vivo. These applications provide comprehensive insights into its potential therapeutic applications, particularly in immunology, inflammatory diseases, and autoimmune disorders.

Immunogen

IL-6

Packaging

100ug/vial; 1mg/vial

Preparation Note

For reconstitution, we recommend adding sterile, distilled water to achieve a final antibody concentration of 1 mg/mL. Gently shake it to solubilize the protein completely. Do not vortex.
Upon receipt, store immediately at -20°C for 24 months in lypholized state. -80°C for 12 months after reconstitution. Avoid repeated freeze-thaw cycles.

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pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H315,H319

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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