SBR00032
MIT HCl
Ready Made Solution, (125-130 mg MIT HCl/mL in water)
Synonym(s):
2-Methyl-1,2-thiazol-3-one hydrochloride, Methylisothiazolinone hydrochloride, MIT HCl Ready Made Solution
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About This Item
UNSPSC Code:
51102829
NACRES:
NA.76
Quality Segment
form
liquid, ready-to-use solution
concentration
(125-130 mg MIT HCl/mL in water)
mode of action
protein synthesis | interferes
storage temp.
2-8°C
InChI
1S/C4H5NOS.ClH/c1-5-4(6)2-3-7-5;/h2-3H,1H3;1H
InChI key
SJXPQSRCFCPWQQ-UHFFFAOYSA-N
General description
Methylisothiazolinone, also known as 2-Methyl-4-isothiazolin-3-one, belongs to the group of isothiazolinones. 2-Methyl-4-isothiazolin-3-one is utilized in microbiology and cell biology applications to effectively prevent the growth of bacterial contaminants, ensuring the purity of cell lines.
Application
Methylisothiazolinone (MIT) has been used:
- in research on the effects of the N-methyl D-aspartate (NMDA) receptor antagonist kynurenic acid on human cortical development [1]
- as a cytotoxic substance to investigate its effect on bronchial epithelial cells (BEAS-2B cells) and role in apoptotic cell death(2)
- to research the effects of tyrosine phosphorylation on focal adhesion kinase (FAK) activity in the development of neural axons and dendrites(3)
Features and Benefits
- Ready available solution reduce the need for preparation time
Other Notes
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Danger
Storage Class
8B - Non-combustible corrosive hazardous materials
flash_point_f
Not applicable
flash_point_c
Not applicable
Hazard Classifications
Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Corr. 1A - Skin Sens. 1
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