SBR00059
Balofloxacin
≥98% (HPLC), powder
InChI
1S/C20H24FN3O4/c1-22-11-4-3-7-23(9-11)17-15(21)8-13-16(19(17)28-2)24(12-5-6-12)10-14(18(13)25)20(26)27/h8,10-12,22H,3-7,9H2,1-2H3,(H,26,27)
InChI key
MGQLHRYJBWGORO-UHFFFAOYSA-N
SMILES string
CNC1CCCN(C1)C2=C(C=C3C(=C2OC)N(C=C(C3=O)C(=O)O)C4CC4)F
assay
≥98% (HPLC)
form
powder
color
off-white
antibiotic activity spectrum
(anaerobic bacteria), Gram-negative bacteria, Gram-positive bacteria
mode of action
DNA synthesis | inhibits
Quality Level
General description
Balofloxacin is a broad spectrum synthetic fluoroquinolone antibiotic. It exerts its antibacterial activity by inhibiting DNA gyrase and topoisomerase IV, which are enzymes essential for bacterial DNA synthesis and replication.
Application
One of the main applications of fluoroquinolones like Balofloxacin is their ability to target and inhibit bacterial DNA gyrase and topoisomerase IV, which are enzymes that are essential for bacterial DNA replication and transcription. Because of their potency against these targets, fluoroquinolones have been used as lead compounds for the development of new antibiotics and other drugs that target these enzymes.
Biochem/physiol Actions
Balofloxacin inhibits bacterial DNA synthesis by interfering with the activity of DNA gyrase and topoisomerase IV enzymes, which are necessary for the replication, transcription, and repair of bacterial DNA. Balofloxacin is active against gram-negative, gram-positive, and anaerobic bacteria.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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