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Merck
CN

SBR00108

Diclofenac Diethylamine

new

≥98%

Synonym(s):

Diclofenac diethylamine salt, N-Ethylethanamine 2-[(2,6-dichlorophenyl)amino]benzeneacetate

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About This Item

Empirical Formula (Hill Notation):
C14H11Cl2NO2· C4H11N
CAS Number:
Molecular Weight:
369.29
UNSPSC Code:
51101500
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Quality Level

Assay

≥98%

form

(powder to crystalline powder)

storage condition

(close container well)

color

white to yellow

mp

153 °C

antibiotic activity spectrum

(bacteria)

Mode of action

enzyme | inhibits

shipped in

ambient

SMILES string

O=C(O)CC=1C=CC=CC1NC=2C(Cl)=CC=CC2Cl.N(CC)CC

InChI

1S/C14H11Cl2NO2.C4H11N/c15-10-5-3-6-11(16)14(10)17-12-7-2-1-4-9(12)8-13(18)19;1-3-5-4-2/h1-7,17H,8H2,(H,18,19);5H,3-4H2,1-2H3

InChI key

ZQVZPANTCLRASL-UHFFFAOYSA-N

General description

Diclofenac Diethylamine is an antibiotic belonging to the class of nonsteroidal anti-inflammatory drugs (NSAIDs).

Application

Diclofenac Diethylamine has been used: - in the research of microemulsions - in the research of the efficacy of matrix-type transdermal patches

Biochem/physiol Actions

Mode of Action: Diclofenac Diethylamine inhibits the enzyme cyclooxygenase (COX).

Antimicrobial Spectrum: Active against bacteria, such as Escherichia coli and Enterobacter aerogenes.

Features and Benefits

High quality antibiotic suitable for mulitple research applications Commonly used in Cell Biology and Biochemical applications

Regulatory Information

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Ljiljana Djordjevic et al.
International journal of pharmaceutics, 296(1-2), 73-79 (2005-05-12)
The purpose of the present study was to determine the influence of both formulation parameters and vehicle structure on in vitro release rate of amphiphilic drug diclofenac diethylamine (DDA) from microemulsion vehicles containing PEG-8 caprylic/capric glycerides (surfactant), polyglyceryl-6 dioleate (cosurfactant)

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