SCP0012
Calmodulin Dependent Protein Kinase II 281-309
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About This Item
Empirical Formula (Hill Notation):
C146H254N46O39S3
Molecular Weight:
3374.06
NACRES:
NA.32
UNSPSC Code:
12352202
Assay:
≥95% (HPLC)
assay
≥95% (HPLC)
form
lyophilized
composition
Peptide Content, ≥65%
storage condition
protect from light
storage temp.
−20°C
Application
Calmodulin Dependent Protein Kinase II 281-309 [CaMK-(281-309)] is a CaMK-peptide used to probe interactions of the various regulatory domains of protein kinase II.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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A Ishida et al.
The Journal of biological chemistry, 270(5), 2163-2170 (1995-02-03)
The active 30-kDa chymotryptic fragment of calmodulin-dependent protein kinase II (CaM kinase II), devoid of the autoinhibitory domain, and the enzyme, autothiophosphorylated at Thr286/Thr287, were much more labile than was the original native enzyme. They were markedly stabilized by synthetic
R J Colbran et al.
The Journal of biological chemistry, 263(34), 18145-18151 (1988-12-05)
Two peptide analogs of Ca2+/calmodulin-dependent protein kinase II (CaMK-(peptides)) were synthesized and used to probe interactions of the various regulatory domains of the kinase. CaMK-(281-289) contained only Thr286, the major Ca2+-dependent autophosphorylation site of the kinase (Schworer, C. M., Colbran
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