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SCP0013

Allatostatin B2 cockroach

Name: Allatostatin B2 cockroach
Brand: SIGMA

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About This Item

Empirical Formula (Hill Notation):

C₁₀₄H₁₅₀N₂₄O₂₇

Molecular Weight:

2168.45

NACRES:

NA.32

UNSPSC Code:

12352200

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Properties

assay

≥95% (HPLC)

form

lyophilized

composition

Peptide Content, ≥75%

storage condition

protect from light

storage temp.

−20°C

Description

Application

Allatostatins are insect and crustacean neuropeptides that inhibit juvenile hormone and reduce food intake. Allostatin B2 (cricket-type), a myoinhibitory peptide (MIP), is used to study the regulation of juvenile hormone production and as a target for insecticide development.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number

BB0106

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Myoinhibitory peptides in the brain of the cockroach Leucophaea maderae and colocalization with pigment-dispersing factor in circadian pacemaker cells.

Julia Schulze et al.

The Journal of comparative neurology, 520(5), 1078-1097 (2011-11-19)

Myoinhibitory peptides (MIPs) are a family of insect W(X(6))Wamides with inhibitory effects on visceral muscles and juvenile hormone synthesis. Although MIPs are widely distributed within the nervous system, a detailed analysis of their distribution and function in insect brains is

Distribution and physiological effects of B-type allatostatins (myoinhibitory peptides, MIPs) in the stomatogastric nervous system of the crab Cancer borealis.

Theresa M Szabo et al.

The Journal of comparative neurology, 519(13), 2658-2676 (2011-04-15)

The crustacean stomatogastric ganglion (STG) is modulated by a large number of amines and neuropeptides that are found in descending pathways from anterior ganglia or reach the STG via the hemolymph. Among these are the allatostatin (AST) B types, also

Molecular cloning, genomic organization, and expression of a B-type (cricket-type) allatostatin preprohormone from Drosophila melanogaster.

M Williamson et al.

Biochemical and biophysical research communications, 281(2), 544-550 (2001-02-22)

The insect allatostatins obtained their names because they block the biosynthesis of juvenile hormone (a terpenoid) in the corpora allata (two endocrine organs near the insect brain). Chemically, the allatostatins can be subdivided into three different peptide groups: the A-type

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Global Trade Item Number

SKU	GTIN
SCP0013-1MG	04061826693049