SCP0160
GRF, mouse
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About This Item
Empirical Formula (Hill Notation):
C220H365N69O64S1
Molecular Weight:
5032.74
UNSPSC Code:
51111800
NACRES:
NA.32
Assay
≥95% (HPLC)
form
lyophilized
composition
Peptide Content, ≥75%
storage condition
protect from light
storage temp.
−20°C
Amino Acid Sequence
His-Val-Asp-Ala-Ile-Phe-Thr-Thr-Asn-Tyr-Arg-Lys-Leu-Leu-Ser-Gln-Leu-Tyr-Ala-Arg-Lys-Val-Ile-Gln-Asp-Ile-Met-Asn-Lys-Gln-Gly-Glu-Arg-Ile-Gln-Glu-Gln-Arg-Ala-Arg-Leu-Ser
Application
Growth Hormone Releasing Factor (GHRF) is an amino acid peptide that induces the release of growth hormone via GPCR receptor GHRH-R.
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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T M Kubiak et al.
Peptide research, 7(3), 153-161 (1994-05-01)
The presence of Val2 in mGRF(1-42)OH is unique and, as shown in this study, renders this GRF resistant to plasma DPP-IV, the main enzyme responsible for rapid hydrolysis and inactivation of Ala2-containing GRFs from other species via cleavages between Ala2-Asp3.
Sjoerd D Joustra et al.
The Journal of clinical endocrinology and metabolism, 105(3) (2019-10-28)
The X-linked immunoglobulin superfamily, member 1 (IGSF1), gene is highly expressed in the hypothalamus and in pituitary cells of the POU1F1 lineage. Human loss-of-function mutations in IGSF1 cause central hypothyroidism, hypoprolactinemia, and macroorchidism. Additionally, most affected adults exhibit higher than
S T Suhr et al.
Molecular endocrinology (Baltimore, Md.), 3(11), 1693-1700 (1989-11-01)
To pursue questions concerning the regulation of somatic growth in a species amenable to both genetics and germ-line manipulation, we have isolated and characterized a full-length cDNA clone encoding mouse GH-releasing hormone (mGHRH). A GHRH cDNA clone isolated from a
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