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Merck
CN

SCP0172

KISS Peptide

≥95% (HPLC), lyophilized powder

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About This Item

Empirical Formula (Hill Notation):
C88H124N24O22
Molecular Weight:
1870.07
UNSPSC Code:
12352202
NACRES:
NA.32
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Product Name

KISS 107-121,

assay

≥95% (HPLC)

form

lyophilized

composition

Peptide Content, ≥75%

storage condition

protect from light

storage temp.

−20°C

Application

Kisspeptins are a family of peptides encoded by the KISS-1 gene that are involved in GPR54 mediated cell signaling. Kiss-1 gene products are involved in metastasis suppression and the regulation of gonadotropin-releasing hormone (GnRH) secretion. A variety of kisspeptin peptides are available for use to study their unique functions.


Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Kisspeptin-GPR54 signaling is essential for preovulatory gonadotropin-releasing hormone neuron activation and the luteinizing hormone surge.
Clarkson J, d'Anglemont de Tassigny X, et al.
The Journal of Neuroscience, 28, 8671-8677 (2008)
Rafael Pineda et al.
Progress in brain research, 181, 55-77 (2010-05-19)
Reproductive maturation and function are maintained by a complex neurohormonal network that integrates at the so-called hypothalamic-pituitary-gonadal (HPG) axis. This system is hierarchically controlled by the decapeptide, GnRH, which in turn is under the dynamic regulation of multiple stimulatory and
Naresh Kumar Hanchate et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 32(3), 932-945 (2012-01-21)
Reproduction is controlled in the brain by a neural network that drives the secretion of gonadotropin-releasing hormone (GnRH). Various permissive homeostatic signals must be integrated to achieve ovulation in mammals. However, the neural events controlling the timely activation of GnRH



Global Trade Item Number

SKUGTIN
SCP0172-1MG04061826693698