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Merck
CN

SCP0186

Metastin, KISS-1 68-121

≥95% (HPLC)

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About This Item

Empirical Formula (Hill Notation):
C258H401N79O78
Molecular Weight:
5857.43
NACRES:
NA.32
UNSPSC Code:
12352200
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assay

≥95% (HPLC)

form

lyophilized

composition

Peptide Content, ≥75%

storage condition

protect from light

storage temp.

−20°C

Application

Kisspeptins are a family of peptides encoded by the KISS-1 gene that are involved in GPR54 mediated cell signaling. Kiss-1 gene products are involved in metastasis suppression and the regulation of gonadotropin-releasing hormone (GnRH) secretion. A variety of kisspeptin peptides are available for use to study their unique functions.


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Rafael Pineda et al.
Progress in brain research, 181, 55-77 (2010-05-19)
Reproductive maturation and function are maintained by a complex neurohormonal network that integrates at the so-called hypothalamic-pituitary-gonadal (HPG) axis. This system is hierarchically controlled by the decapeptide, GnRH, which in turn is under the dynamic regulation of multiple stimulatory and
Naresh Kumar Hanchate et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 32(3), 932-945 (2012-01-21)
Reproduction is controlled in the brain by a neural network that drives the secretion of gonadotropin-releasing hormone (GnRH). Various permissive homeostatic signals must be integrated to achieve ovulation in mammals. However, the neural events controlling the timely activation of GnRH
Jenny Clarkson et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 28(35), 8691-8697 (2008-08-30)
Kisspeptin and its receptor GPR54 have recently been identified as key signaling partners in the neural control of fertility in animal models and humans. The gonadotropin-releasing hormone (GnRH) neurons represent the final output neurons of the neural network controlling fertility



Global Trade Item Number

SKUGTIN
SCP0186-1MG04061826693766
SCP0186-500UG04061837017643