SMB00207
Cornuside
≥95% (LC/MS-ELSD)
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About This Item
Empirical Formula (Hill Notation):
C24H30O14
CAS Number:
Molecular Weight:
542.49
NACRES:
NA.25
UNSPSC Code:
12352200
MDL number:
assay
≥95% (LC/MS-ELSD)
form
solid
application(s)
metabolomics
vitamins, nutraceuticals, and natural products
storage temp.
−20°C
InChI
1S/C24H30O14/c1-3-11-12(4-5-35-21(32)10-6-14(26)17(28)15(27)7-10)13(22(33)34-2)9-36-23(11)38-24-20(31)19(30)18(29)16(8-25)37-24/h3,6-7,9,11-12,16,18-20,23-31H,1,4-5,8H2,2H3/t11-,12+,16+,18+,19-,20+,23+,24-/m0/s1
InChI key
SMTKSCGLXONVGL-ZEIULZLQSA-N
General description
Natural product derived from plant source.
Biochem/physiol Actions
Cornuside is a secoiridoid glucoside with anti-inflammatory properties through the downregulation of iNOS and COX-2 via NF-kB inhibition.
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Shun Zong Song et al.
Bioscience, biotechnology, and biochemistry, 75(4), 656-661 (2011-04-23)
This study elucidated the effects of cornuside on carbon tetrachloride (CCl₄)-induced hepatotoxicity. Rats were treated intraperitoneally with 0.5 mL/kg of CCl₄. Sixteen h after CCl₄ treatment, the levels of serum aminotransferases, tumor necrosis factor-α (TNF-α), and lipid peroxidation were significantly
S P Zhao et al.
Yao xue xue bao = Acta pharmaceutica Sinica, 27(11), 845-848 (1992-01-01)
A new bisiridoid glucoside named cornuside was isolated from the fruits of Cornus officinalis Sieb et Zucc. The structure of cornuside has been established by spectroscopic methods (IR, MS, 1HNMR, 13CNMR).
Wang-Lin Jiang et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 18(4), 266-271 (2010-08-27)
Cornuside is a secoiridoid glucoside isolated from the fruit of Cornus officinalis SIEB. et ZUCC. In this study, we investigated the anti-myocardial ischemia and reperfusion (I/R) injury effects of cornuside in vivo and elucidated the potential mechanism. Rat models of
Global Trade Item Number
| SKU | GTIN |
|---|---|
| SMB00207-1MG | 04061826169124 |