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SMB01005

Salvianolic acid B

≥85% (LC/MS-ELSD)

Synonym(s):

Lithospermic acid B, Salvianic acid B

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About This Item

Empirical Formula (Hill Notation):
C36H30O16
CAS Number:
115939-25-8
Molecular Weight:
718.61
UNSPSC Code:
12352205
NACRES:
NA.25
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biological source

plant

assay

≥85% (LC/MS-ELSD)

form

solid

mol wt

718.61

color

light yellow to brown

solubility

water: soluble

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

storage temp.

−20°C

SMILES string

O1[C@H]([C@@H](c4c1c(ccc4\C=C\C(=O)O[C@H](Cc5cc(c(cc5)O)O)C(=O)O)O)C(=O)O[C@H](Cc3cc(c(cc3)O)O)C(=O)O)c2cc(c(cc2)O)O

InChI

1S/C36H30O16/c37-20-6-1-16(11-24(20)41)13-27(34(45)46)50-29(44)10-5-18-3-9-23(40)33-30(18)31(32(52-33)19-4-8-22(39)26(43)15-19)36(49)51-28(35(47)48)14-17-2-7-21(38)25(42)12-17/h1-12,15,27-28,31-32,37-43H,13-14H2,(H,45,46)(H,47,48)/b10-5+/t27-,28-,31-,32+/m1/s1

InChI key

SNKFFCBZYFGCQN-PDVBOLEISA-N

General description

Salvianolic acid B, also known as Lithospermic acid B, is a polyphenol and a member of catechols. This bioactive natural compound is commonly found in plants such as Salvia Sp., Isodon rubescens, Mentha Sp., Canna indica, and Angelica keiskei. Existing research suggests that this plant-derived natural product possesses a range of biological properties, including anticancer, anti-inflammatory, hepatoprotective, cardioprotective and neuroprotective activities.

Application

It is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.

Biochem/physiol Actions

According to the existing research, Salvianolic acid B plays potential role in modulating inflammation, cell signaling, and immune responses by inhibiting the expression of COX, ERK, TNF-α, NO.
Salvianolic acid B has anti-obesity, antiviral (COVID-19) and free radical scavenging activity.

Features and Benefits

  • High quality compound suitable for multiple research applications
  • Compatible with HPLC and mass spectrometry techniques

Other Notes

For additional information on our range of Biochemicals, please complete this form.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Lin Li et al.
Food & function, 11(10), 8743-8756 (2020-09-22)
Salvianolic acid B (Sal B) exhibits anti-obesity activity, yet the underlying mechanism linking this effect to metabolic endotoxemia remains unexplored. For this purpose, high-fat diet-induced obese mice were orally administered with Sal B for 10 weeks. Hematoxylin/eosin staining, transmission electron
Repurposing approved drugs as potential inhibitors of 3CL-protease of SARS-CoV-2: Virtual screening and structure based drug design
Almes F J, et al.
Computational Biology and Chemistry, 88, 107351-107351 (2020)
Annarita Viggiano et al.
Applied and environmental microbiology, 84(4) (2017-12-03)
Chrysogine is a yellow pigment produced by Penicillium chrysogenum and other filamentous fungi. Although the pigment was first isolated in 1973, its biosynthetic pathway has so far not been resolved. Here, we show that deletion of the highly expressed nonribosomal