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About This Item
Empirical Formula (Hill Notation):
C10H8O5 · xH2O
CAS Number:
Molecular Weight:
208.17 (anhydrous basis)
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
Assay
≥98% (HPLC)
form
powder
storage condition
desiccated
color
white to tan
solubility
DMSO: ≥24 mg/mL
storage temp.
2-8°C
SMILES string
O.CC(=O)C(=O)Oc1ccccc1C(O)=O
InChI
1S/C10H8O5.H2O/c1-6(11)10(14)15-8-5-3-2-4-7(8)9(12)13;/h2-5H,1H3,(H,12,13);1H2
InChI key
DLKFQAHWYMEWIK-UHFFFAOYSA-N
Application
OBA-09 hydrate may be used in cell signaling studies.
Biochem/physiol Actions
Neuroprotective agent
OBA-09 is a neuroprotective agent. It is an ester of pyruvate and salicylic acid that acts as a multi-functional agent to protect against ischemic damages to the brain. Administration of 5 mpk OBA-09 following middle cerebral artery occlusion (MCAO) or oxygen-glucose deprivation (OGD) models of ischemic injury in rats prevents lipid peroxidation, ROS production and causes the recovery of NAD and ATP concentrations to near basal levels. The compound leads to reduction of infarct volume and also accelerates the recovery of behavioral and neurological deficits.
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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