SML0126
OBA-09 hydrate
≥98% (HPLC)
Synonym(s):
2-(1,2-Dioxopropoxy)benzoic acid hydrate, O-Pyruvoylsalicylic acid hydrate
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About This Item
Empirical Formula (Hill Notation):
C10H8O5 · xH2O
CAS Number:
Molecular Weight:
208.17 (anhydrous basis)
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
SMILES string
O.CC(=O)C(=O)Oc1ccccc1C(O)=O
InChI
1S/C10H8O5.H2O/c1-6(11)10(14)15-8-5-3-2-4-7(8)9(12)13;/h2-5H,1H3,(H,12,13);1H2
InChI key
DLKFQAHWYMEWIK-UHFFFAOYSA-N
assay
≥98% (HPLC)
form
powder
storage condition
desiccated
color
white to tan
solubility
DMSO: ≥24 mg/mL
storage temp.
2-8°C
Application
OBA-09 hydrate may be used in cell signaling studies.
Biochem/physiol Actions
Neuroprotective agent
OBA-09 is a neuroprotective agent. It is an ester of pyruvate and salicylic acid that acts as a multi-functional agent to protect against ischemic damages to the brain. Administration of 5 mpk OBA-09 following middle cerebral artery occlusion (MCAO) or oxygen-glucose deprivation (OGD) models of ischemic injury in rats prevents lipid peroxidation, ROS production and causes the recovery of NAD and ATP concentrations to near basal levels. The compound leads to reduction of infarct volume and also accelerates the recovery of behavioral and neurological deficits.
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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