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Merck
CN

SML0163

Sigma-Aldrich

Beta-3 Adrenoceptor Partial Agonist (β3-633-AG) synthetic

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About This Item

Empirical Formula (Hill Notation):
C50H55BF2N6O7S
Molecular Weight:
932.88
UNSPSC Code:
51111800
NACRES:
NA.77
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Assay

≥97% (HPLC)

Quality Level

storage temp.

−20°C

Biochem/physiol Actions

This ligand is a partial agonist at β3 adrenoceptors, is a very weak partial agonist at β1, and has no agonist activity at β2. It also acts as an antagonist at β1, β2 and β3.

Features and Benefits

This compound is featured on the β-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Preparation Note

Dissolve 0.2 mg in 21.4 ul of DMSO to give a 10mM stock solution. Once reconstituted into DMSO the product, must be stored, preferably in smaller aliquots, at -20°C.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Articles

β-Adrenoceptors are activated either by norepinephrine or epinephrine. Learn more about the role of β-adrenoceptors in protein expression, cell signaling, and metabolism research.

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