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Merck
CN

SML0380

FMP-API-1

≥98% (HPLC)

Synonym(s):

3,3′-Diamino-4,4′-dihydroxydiphenylmethane, 4,4′-Methylenebis(2-aminophenol), Bis(3-amino-4-hydroxyphenyl)methane

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About This Item

Empirical Formula (Hill Notation):
C13H14N2O2
CAS Number:
Molecular Weight:
230.26
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
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assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: >10 mg/mL

storage temp.

−20°C

SMILES string

Nc1cc(Cc2ccc(O)c(N)c2)ccc1O

InChI

1S/C13H14N2O2/c14-10-6-8(1-3-12(10)16)5-9-2-4-13(17)11(15)7-9/h1-4,6-7,16-17H,5,14-15H2

InChI key

KCFVSHSJPIVGCG-UHFFFAOYSA-N

Biochem/physiol Actions

FMP-API-1 is an inhibitor of AKAP-PKA interactions in vitro and in cultured cardiac myocytes that activates PKA. Apparently, FMP-API-1 binds to a novel allosteric regulatory site.
FMP-API-1 is an inhibitor of AKAP-PKA interactions.

Features and Benefits

This compound is featured on the PKA & PKG page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Other Notes

Air Sensitive


pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2 - Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Articles

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Louis-Philippe Bernier et al.
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Global Trade Item Number

SKUGTIN
SML0380-25MG04061833222607
SML0380-5MG04061833222614