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Merck
CN

SML0403

Sigma-Aldrich

GW542573X

≥98% (HPLC)

Synonym(s):

4-(2-Methoxy-phenylcarbamoyloxymethyl)-piperidine-1-carboxylic acid tert-butyl ester

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About This Item

Empirical Formula (Hill Notation):
C19H28N2O5
CAS Number:
660846-41-3
Molecular Weight:
364.44
MDL number:
MFCD20926353
UNSPSC Code:
12352200
PubChem Substance ID:
329825399
NACRES:
NA.77

Key Documents

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Assay

≥98% (HPLC)

form

oil

color

colorless to yellow

storage temp.

2-8°C

SMILES string

COc1ccccc1NC(=O)OCC2CCN(CC2)C(=O)OC(C)(C)C

InChI

1S/C19H28N2O5/c1-19(2,3)26-18(23)21-11-9-14(10-12-21)13-25-17(22)20-15-7-5-6-8-16(15)24-4/h5-8,14H,9-13H2,1-4H3,(H,20,22)

InChI key

SAXGSDIZIYFNKD-UHFFFAOYSA-N

Biochem/physiol Actions

GW542573X is a selective SK1 activator.
GW542573X is a very selective activator of the small conductance calcium-activated potassium channel SK1 (KCa2.1).

Features and Benefits

This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Pictograms

Environment
GHS09

Signal Word

Warning

Hazard Statements

H410

Precautionary Statements

P273 - P501

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
062M4630V

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