SML0463
BPD
≥98% (HPLC)
Synonym(s):
3-(1,3-benzodioxol-5-yl)-4-phenyl-2,5-Furandione
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About This Item
Empirical Formula (Hill Notation):
C17H10O5
CAS Number:
Molecular Weight:
294.26
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated
assay
≥98% (HPLC)
form
powder
storage condition
desiccated
color
white to beige
solubility
DMSO: 15 mg/mL (clear solution)
storage temp.
−20°C
SMILES string
O=C1OC(=O)C(c2ccc3OCOc3c2)=C1c4ccccc4
InChI
1S/C17H10O5/c18-16-14(10-4-2-1-3-5-10)15(17(19)22-16)11-6-7-12-13(8-11)21-9-20-12/h1-8H,9H2
InChI key
IMHGOAWBSJVILI-UHFFFAOYSA-N
Biochem/physiol Actions
BPD inhibits LPS-induced NF-kB signaling by inactivation of TAK-1. BPD is also known to inhibit the expression and activity of COX-2.
BPD inhibits LPS-induced NF-kB signaling; COX-2 inhibitor.
Features and Benefits
This compound is featured on the Cytokine Receptors (Interleukin-1 Receptor/TIR Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Acute 1
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Anna Karin Edstedt Bonamy et al.
Archives of disease in childhood. Fetal and neonatal edition, 104(1), F36-F45 (2018-01-22)
To investigate the variation in severe neonatal morbidity among very preterm (VPT) infants across European regions and whether morbidity rates are higher in regions with low compared with high mortality rates. Area-based cohort study of all births before 32 weeks
Sebastian Euler et al.
Frontiers in psychology, 9, 824-824 (2018-06-19)
Interpersonal sensitivity, particularly threat of potential exclusion, is a critical condition in borderline personality disorder (BPD) which impairs patients' social adjustment. Current evidence-based treatments include group components, such as mentalization-based group therapy (MBT-G), in order to improve interpersonal functioning. These
Jennifer Sophie Landry et al.
Annals of the American Thoracic Society, 13(1), 17-24 (2015-11-03)
Bronchopulmonary dysplasia and the long-term consequences of prematurity are underrecognized entities, unfamiliar to adult clinicians. Well described by the pediatric community, these young adults are joining the ranks of a growing population of adults with chronic lung disease. To describe
Global Trade Item Number
| SKU | GTIN |
|---|---|
| SML0463-25MG | 04061832261218 |
| SML0463-5MG | 04061832786599 |