SML0503
9(S)-HODE
≥98% (HPLC), metabolite of linoleic acid, solution
Synonym(s):
9S-Hydroxy-10E,12Z-octadecadienoic acid
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About This Item
Empirical Formula (Hill Notation):
C18H32O3
CAS Number:
Molecular Weight:
296.44
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
51111800
EC Number:
200-578-6
MDL number:
Assay:
≥98% (HPLC)
Form:
solution
Product Name
9(S)-HODE, ≥98% (HPLC)
Quality Segment
assay
≥98% (HPLC)
form
solution
concentration
1 mg/mL in ethanol
color
colorless to light yellow
shipped in
wet ice
storage temp.
−20°C
SMILES string
CCCCC/C=C\C=C\[C@@H](O)CCCCCCCC(O)=O
InChI
1S/C18H32O3/c1-2-3-4-5-6-8-11-14-17(19)15-12-9-7-10-13-16-18(20)21/h6,8,11,14,17,19H,2-5,7,9-10,12-13,15-16H2,1H3,(H,20,21)/b8-6-,14-11+/t17-/m1/s1
InChI key
NPDSHTNEKLQQIJ-UINYOVNOSA-N
Biochem/physiol Actions
9(S)-HODE is a pro-inflammatory linoleic acid lipoxygenation product.
9(S)-HODE is produced by the lipoxygenation of linoleic acid. It is a major component of plasma oxidized low-density lipoprotein. 9-HODE has been shown to stimulate cell proliferation and and extracellular matrix synthesis in human mesangial cells via PPARgamma. Pro-inflammatory effects of 9-HODE, acting through the receptor GPR132, can contribute to atherosclerosis progression. 9-HODE has also been shown to activate spinal TRPV1, leading to inflammatory hyperalgesia.
Disclaimer
Supply conditions do not apply to the regions and states of Brazil: North, Northeast, Mato Grosso do Sul, Mato Grosso, and Rio Grande do Sul.
signalword
Danger
hcodes
Hazard Classifications
Eye Irrit. 2 - Flam. Liq. 2
Storage Class
3 - Flammable liquids
wgk
WGK 1
flash_point_f
57.2 °F - closed cup
flash_point_c
14.0 °C - closed cup
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