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Merck
CN

SML0512

BLT-4

≥98% (HPLC)

Synonym(s):

INF 271, MIT 9952-29, N-(2-Methoxyphenyl)-N′-2-naphthalenyl-urea

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About This Item

Empirical Formula (Hill Notation):
C18H16N2O2
CAS Number:
Molecular Weight:
292.33
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
51111800
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
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Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 15 mg/mL (clear solution)

storage temp.

room temp

SMILES string

COc1ccccc1NC(=O)Nc2ccc3ccccc3c2

InChI

1S/C18H16N2O2/c1-22-17-9-5-4-8-16(17)20-18(21)19-15-11-10-13-6-2-3-7-14(13)12-15/h2-12H,1H3,(H2,19,20,21)

InChI key

ISADADAHPHHLEM-UHFFFAOYSA-N

Biochem/physiol Actions

BLT-4 is a SR-BI (Scavenger receptor, class B, type I) inhibitor.
BLT-4 is a blocker of lipid transport-4 (BLT-4). BLT-4 is a specific, reversible inhibitor of scavenger receptor, class B, type I (SR-BI) mediated lipid transfer. The molecule blocks the cellular uptake and transfer of cholesterol ester from HDL.


pictograms

Environment

signalword

Warning

hcodes

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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