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Merck
CN

SML0643

Sigma-Aldrich

M617 trifluoroacetate salt

≥95% (HPLC)

Synonym(s):

Galanin(1-13)-Gln14-bradykinin(2-9)amide trifluoroacetate salt

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About This Item

Empirical Formula (Hill Notation):
C112H161N29O28 · xC2HF3O2
CAS Number:
860790-38-1
Molecular Weight:
2361.65 (free base basis)
UNSPSC Code:
12352202

Key Documents

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Assay

≥95% (HPLC)

form

powder

color

white to beige

shipped in

wet ice

storage temp.

−20°C

InChI

1S/C112H161N29O28/c1-59(2)44-73(130-97(155)74(45-60(3)4)131-99(157)77(49-66-33-35-68(145)36-34-66)127-90(149)54-121-95(153)62(7)124-104(162)81(57-142)135-102(160)80(51-88(115)147)132-98(156)75(46-61(5)6)134-108(166)93(63(8)144)137-103(161)79(125-89(148)52-113)50-67-53-120-70-27-16-15-26-69(67)70)96(154)123-56-92(151)138-40-18-30-84(138)106(164)129-72(37-38-87(114)146)109(167)141-43-21-32-86(141)111(169)140-42-19-29-83(140)105(163)122-55-91(150)126-76(47-64-22-11-9-12-23-64)100(158)136-82(58-143)110(168)139-41-20-31-85(139)107(165)133-78(48-65-24-13-10-14-25-65)101(159)128-71(94(116)152)28-17-39-119-112(117)118/h9-16,22-27,33-36,53,59-63,71-86,93,120,142-145H,17-21,28-32,37-52,54-58,113H2,1-8H3,(H2,114,146)(H2,115,147)(H2,116,152)(H,121,153)(H,122,163)(H,123,154)(H,124,162)(H,125,148)(H,126,150)(H,127,149)(H,128,159)(H,129,164)(H,130,155)(H,131,157)(H,132,156)(H,133,165)(H,134,166)(H,135,160)(H,136,158)(H,137,161)(H4,117,118,119)/t62-,63+,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-,82-,83-,84-,85-,86-,93-/m0/s1

InChI key

PAYBRARNTYCYOT-OTTBQUPZSA-N

Amino Acid Sequence

GLY-TRP-THR-LEU-ASN-SER-ALA-GLY-TYR-LEU-LEU-GLY-PRO-GLN-PRO-PRO-GLY-PHE-SER-PRO-PHE-ARG-NH2 trifluoroacetate salt

Biochem/physiol Actions

M617, galanin(1–13)-Gln14-bradykinin(2–9)amide, is a chimeric peptide that acts as a selective agonist for the Galanin GalR1 receptor. M617 shows 25-fold specificity for GalR1with Ki values of 0.23 for GAL1 and 5.71 nM for GAL2.
M617is a Galanin GalR1 selective agonist.

Features and Benefits

This compound is featured on the Galanin Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
033M4737V

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