Skip to Content
Merck
CN

SML0707

Sigma-Aldrich

FKGK11

≥98% (GC)

Synonym(s):

1,1,1,2,2-Pentafluoro-7-phenyl-3-Heptanone

Sign Into View Organizational & Contract Pricing

Select a Size

About This Item

Empirical Formula (Hill Notation):
C13H13F5O
CAS Number:
1071000-98-0
Molecular Weight:
280.23
UNSPSC Code:
41106300
NACRES:
NA.77

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Assay

≥98% (GC)

form

oil

color

colorless to yellow

shipped in

wet ice

storage temp.

−20°C

InChI

1S/C13H13F5O/c14-12(15,13(16,17)18)11(19)9-5-4-8-10-6-2-1-3-7-10/h1-3,6-7H,4-5,8-9H2

InChI key

ROPVXAWEVYWEQY-UHFFFAOYSA-N

Biochem/physiol Actions

FKGK11 is a potent inhibitor of GVIA iPLA2 with little or no inhibition against GIVA cPLA2 (XI(50) = 0.0073 and >0.91, respectively).
FKGK11 is a potent inhibitor of GVIA iPLA2 with little or no inhibition against GIVA cPLA2 (XI(50) = 0.0073 and >0.91, respectively). The compound displays a slight inhibition against GVsPLA2. FKGK11 potently inhibited the progression and severity in a murine experimental autoimmune encephalomyelitis (EAE) model.

Features and Benefits

This compound is featured on the Phospholipase A2 page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Other Notes

Air sensitive; suggest to store under nitrogen in freezer.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

新产品
This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
053M4608V

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Articles

Phospholipase A2

Phospholipase A2 (PLA2) enzymes hydrolyze glycerophospholipids, yielding arachidonic acid; inhibition targets eicosanoid biosynthesis.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service