SML0747
HHQ
≥98% (HPLC)
Synonym(s):
2-Heptyl-4-quinolone
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About This Item
Empirical Formula (Hill Notation):
C16H21NO
CAS Number:
Molecular Weight:
243.34
UNSPSC Code:
12352200
NACRES:
NA.77
Product Name
HHQ, ≥98% (HPLC)
SMILES string
[nH]1c2c([c](cc1CCCCCCC)=O)cccc2
InChI
1S/C16H21NO/c1-2-3-4-5-6-9-13-12-16(18)14-10-7-8-11-15(14)17-13/h7-8,10-12H,2-6,9H2,1H3,(H,17,18)
InChI key
UYRHHBXYXSYGHA-UHFFFAOYSA-N
assay
≥98% (HPLC)
form
powder
storage condition
protect from light
color
white to beige
solubility
DMSO: 5 mg/mL, clear
storage temp.
2-8°C
Quality Level
Biochem/physiol Actions
HHQ or 2-Heptyl-4-quinolone is a modulator of swarm motility. HHQ can be converted to PQS (Pseudomonas quinolone signal) by the PqsH protein.
HHQ s a modulator of swarm motility.
HHQ stimulates vesicle formation but not as much as PQS.
General description
HHQ belongs to 2-alkyl-4-quinolone compounds, which are lipophilic and are slightly soluble in water.
Other Notes
Light sensitive
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Pseudomonas: Volume 6: Molecular Microbiology, Infection and Biodiversity. (2010)
The Pseudomonas aeruginosa 4-quinolone signal molecules HHQ and PQS play multifunctional roles in quorum sensing and iron entrapment.
Diggle S P, et al.
Chemistry & Biology, 14(1), 87-96 (2007)
Jennifer R Klaus et al.
Applied and environmental microbiology, 86(24) (2020-10-04)
The bacterium Burkholderia thailandensis produces an arsenal of secondary metabolites that have diverse structures and roles in the ecology of this soil-dwelling bacterium. In coculture experiments, B. thailandensis strain E264 secretes an antimicrobial that nearly eliminates another soil bacterium, Bacillus
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