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Merck
CN

SML0852

CC4

≥98% (HPLC)

Synonym(s):

(1R,5S)-1,2,3,4,5,6-Hexahydro-3-[2-[(1R,5S)-1,5,6,8-tetrahydro-8-oxo-1,5-methano-2H-pyrido[1,2-a][1,5]diazocin-3(4H)-yl]ethyl]-1,5-Methano-8H-pyrido[1,2-a][1,5]diazocin-8-one, 1,2-BisN-cytisinylethane

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About This Item

Empirical Formula (Hill Notation):
C24H30N4O2
CAS Number:
Molecular Weight:
406.52
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
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assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

H2O: 5 mg/mL, clear (warmed)

storage temp.

2-8°C

InChI

1S/C24H30N4O2/c29-23-5-1-3-21-19-9-17(13-27(21)23)11-25(15-19)7-8-26-12-18-10-20(16-26)22-4-2-6-24(30)28(22)14-18/h1-6,17-20H,7-16H2/t17-,18-,19+,20+/m0/s1

InChI key

LEXDAVFCJPDCNA-VNTMZGSJSA-N

Biochem/physiol Actions

CC4 is a a partial agonist of α4β2 and α6β2 nicotinic acetylcholine receptors with low affinity for α3β4 and α7 containing receptors. CC4 reduces nicotine-induced self-administration and conditioned place preference without affecting motor functions.
CC4 is a a partial agonist of α4β2 and α6β2 nicotinic acetylcholine receptors.

Features and Benefits

This compound is featured on the Acetylcholine Receptors (Nicotinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.


pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Articles

Sigma-Aldrich offers many products related to nicotinic acetylcholine receptors for your research needs.

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Global Trade Item Number

SKUGTIN
SML0852-5MG04061833224113
SML0852-25MG04061833224106