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Merck
CN

SML0855

Sigma-Aldrich

GW438014A

≥98% (HPLC)

Synonym(s):

GW 438014A, N-[1-(2-Phenylethyl)-1H-benzimidazol-2-yl]-benzamide monomethanesulfonate (9CI)

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About This Item

Empirical Formula (Hill Notation):
C22H19N3O · CH3SO3H
CAS Number:
469861-49-2
Molecular Weight:
437.51
UNSPSC Code:
12352200

Key Documents

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Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 20 mg/mL, clear

storage temp.

2-8°C

InChI

1S/C22H19N3O.CH4O3S/c26-21(18-11-5-2-6-12-18)24-22-23-19-13-7-8-14-20(19)25(22)16-15-17-9-3-1-4-10-17;1-5(2,3)4/h1-14H,15-16H2,(H,23,24,26);1H3,(H,2,3,4)

InChI key

AVYFZOKRFCFQLP-UHFFFAOYSA-N

Biochem/physiol Actions

GW438014A is a potent and selective neuropeptide Y Y5 receptor antagonist.
GW438014A is a potent and selective neuropeptide Y Y5 receptor antagonist. GW438014A induces a potent reduction of food intake in rodents.

Features and Benefits

This compound is featured on the Neuropeptide Y Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Pictograms

Skull and crossbones
GHS06

Signal Word

Danger

Hazard Statements

H301

Precautionary Statements

P301 + P310

Hazard Classifications

Acute Tox. 3 Oral

Storage Class Code

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
103M4608V

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