SML0894
VU0420373
≥98% (HPLC)
Synonym(s):
2-[5-(2-Fluorophenyl)-1H-pyrazol-3-yl]-phenol
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About This Item
Empirical Formula (Hill Notation):
C15H11FN2O
CAS Number:
Molecular Weight:
254.26
UNSPSC Code:
12352200
NACRES:
NA.77
Assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 20 mg/mg protein, clear
storage temp.
2-8°C
Biochem/physiol Actions
VU0420373 is an activator of the heme sensor system (HssRS) in S. aureus.
VU0420373 is an activator of the heme sensor system (HssRS) in Staphylococcus aureus. The compound VU0420373 induces heme biosynthesis, and is toxic to fermenting S. aureus. VU0420373 reduces the number of liver abscesses, and tissue damage in S. aureus infected mice.
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