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Merck
CN

SML0938

Sigma-Aldrich

Dofequidar fumarate

≥98% (HPLC)

Synonym(s):

4-(Diphenylacetyl)-a-[(5-quinolinyloxy)methyl]-1-Piperazineethanol (E)-2-butenedioate fumarate (1:1.5), MS-209 fumarate

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About This Item

Empirical Formula (Hill Notation):
C30H31N3O3 · 1.5 C4H4O4
CAS Number:
Molecular Weight:
655.69
UNSPSC Code:
12161501
NACRES:
NA.77
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Assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

DMSO: 20 mg/mL, clear

storage temp.

−20°C

InChI

1S/2C30H31N3O3.3C4H4O4/c2*34-25(22-36-28-15-7-14-27-26(28)13-8-16-31-27)21-32-17-19-33(20-18-32)30(35)29(23-9-3-1-4-10-23)24-11-5-2-6-12-24;3*5-3(6)1-2-4(7)8/h2*1-16,25,29,34H,17-22H2;3*1-2H,(H,5,6)(H,7,8)/b;;3*2-1+

InChI key

ZGMJYTYLTJFNCS-VQYXCCSOSA-N

Biochem/physiol Actions

Dofequidar fumarate is a potent inhibitor of MDR-1.
Dofequidar fumarate is a potent inhibitor of MDR-1. The compound Dofequidar fumarate sensitizes tumor cells to cytotoxic drugs.

Features and Benefits

This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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