SML0966
PLX647
≥98% (HPLC)
Synonym(s):
5-(1H-Pyrrolo[2,3-b]pyridin-3-ylmethyl)-N-[[4-(trifluoromethyl)phenyl]methyl]-2-pyridinamine
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About This Item
Empirical Formula (Hill Notation):
C21H17F3N4
CAS Number:
Molecular Weight:
382.38
NACRES:
NA.77
UNSPSC Code:
12352200
Assay:
≥98% (HPLC)
Form:
powder
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 20 mg/mL, clear
storage temp.
2-8°C
Biochem/physiol Actions
PLX647 is a potent and specific dual inhibitor of the receptor tyrosine kinases FMS and KIT.
PLX647 is a potent and specific dual inhibitor of the receptor tyrosine kinases FMS and KIT. PLX647 blocks activation of macrophages, osteoclasts and mast cells in both cell based and in vivo inflammation models.
Features and Benefits
This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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