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Merck
CN

SML1029

KP372-1

≥98% (HPLC)

Synonym(s):

10H-Indeno[2,1-e]tetrazolo[1,5-b][1,2,4]triazin-10-one (1:1), 6H-Indeno[1,2-e]tetrazolo[1,5-b][1,2,4]triazin-6-one

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About This Item

Empirical Formula (Hill Notation):
C10H4N6O
CAS Number:
Molecular Weight:
224.18
NACRES:
NA.77
UNSPSC Code:
12352200
Assay:
≥98% (HPLC)
Form:
powder
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description

1:1 mixture of two isomers

assay

≥98% (HPLC)

form

powder

color

light yellow to dark yellow

solubility

DMSO: 10 mg/mL, clear

storage temp.

2-8°C

Biochem/physiol Actions

KP372-1 is a potent inhibitor of AKT and PKD.
KP372-1 is a potent inhibitor of AKT and PKD. KP-372-1 blocks PI3K/AKT/mTOR signaling pathways, and induces apoptosis in leukemia cell lines and primary tumor cells from patients with AML.

signalword

Danger

pictograms

Flame

hcodes

Hazard Classifications

Self-react. C

Storage Class

5.2 - Organic peroxides and self-reacting hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

新产品

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Global Trade Item Number

SKUGTIN
SML1029-25MG04061832451367
SML1029-5MG04061832451374

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