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Merck
CN

SML1156

NID-1

≥98% (HPLC)

Synonym(s):

N-(2-Ethylphenyl)-3-(5-nitro-2-thienyl)- 2-propenamide

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About This Item

Empirical Formula (Hill Notation):
C15H14N2O3S
CAS Number:
Molecular Weight:
302.35
PubChem Substance ID:
UNSPSC Code:
12352200
Assay:
≥98% (HPLC)
Form:
powder
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assay

≥98% (HPLC)

form

powder

color

faintly yellow to dark yellow

solubility

DMSO: 25 mg/mL, clear

storage temp.

2-8°C

SMILES string

O=C(NC1=CC=CC=C1CC)/C=C/C2=CC=C([N+]([O-])=O)S2

InChI

1S/C15H14N2O3S/c1-2-11-5-3-4-6-13(11)16-14(18)9-7-12-8-10-15(21-12)17(19)20/h3-10H,2H2,1H3,(H,16,18)/b9-7+

InChI key

YTQHWWVZNNZOIK-VQHVLOKHSA-N

Biochem/physiol Actions

NID-1 (Novel Inducer of Death-1) is a cell permeable and potent inducer of energy-dependent non-apoptotic cell death in mammalian cell lines. NID-1 induced cell death is distinct from macroautophagy, but still reacquires ATG5 and the lysosomal hydrolase cathepsin-L.
NID-1 is a cell permeable and potent inducer of energy-dependent non-apoptotic cell death in mammalian cell lines.


Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Global Trade Item Number

SKUGTIN
SML1156-25MG04061832926278
SML1156-5MG04061832926285