SML1156
NID-1
≥98% (HPLC)
Synonym(s):
N-(2-Ethylphenyl)-3-(5-nitro-2-thienyl)- 2-propenamide
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About This Item
Empirical Formula (Hill Notation):
C15H14N2O3S
CAS Number:
Molecular Weight:
302.35
PubChem Substance ID:
UNSPSC Code:
12352200
InChI
1S/C15H14N2O3S/c1-2-11-5-3-4-6-13(11)16-14(18)9-7-12-8-10-15(21-12)17(19)20/h3-10H,2H2,1H3,(H,16,18)/b9-7+
InChI key
YTQHWWVZNNZOIK-VQHVLOKHSA-N
SMILES string
O=C(NC1=CC=CC=C1CC)/C=C/C2=CC=C([N+]([O-])=O)S2
assay
≥98% (HPLC)
form
powder
color
faintly yellow to dark yellow
solubility
DMSO: 25 mg/mL, clear
storage temp.
2-8°C
Biochem/physiol Actions
NID-1 (Novel Inducer of Death-1) is a cell permeable and potent inducer of energy-dependent non-apoptotic cell death in mammalian cell lines. NID-1 induced cell death is distinct from macroautophagy, but still reacquires ATG5 and the lysosomal hydrolase cathepsin-L.
NID-1 is a cell permeable and potent inducer of energy-dependent non-apoptotic cell death in mammalian cell lines.
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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