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Merck
CN

SML1178

NDMC101

≥98% (HPLC)

Synonym(s):

HS-Cm, N-(4-Chloro-2-fluorophenyl)-2-hydroxybenzamide

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About This Item

Empirical Formula (Hill Notation):
C13H9ClFNO2
CAS Number:
Molecular Weight:
265.67
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
51111800
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
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assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 20 mg/mL, clear

storage temp.

2-8°C

SMILES string

O=C(NC1=C(F)C=C(Cl)C=C1)C2=CC=CC=C2O

InChI

1S/C13H9ClFNO2/c14-8-5-6-11(10(15)7-8)16-13(18)9-3-1-2-4-12(9)17/h1-7,17H,(H,16,18)

InChI key

NUQWCDAXACRITO-UHFFFAOYSA-N

Biochem/physiol Actions

NDMC101 (HS Cm) is a potent dipeptidyl peptidase-IV (DPPIV) inhibitor in T cells with low cytotoxicity. NDMC101 is a potent immunomodulator that inhibits production of IL-2, TNF-α and IFN-γ. NDMC101 inhibits osteoclastogenesis in experimental model of arthritis.
NDMC101 is a potent dipeptidyl peptidase-IV (DPPIV) inhibitor in T cells.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Global Trade Item Number

SKUGTIN
SML1178-5MG04061832868400
SML1178-25MG04061833034101

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