SML1203
2-PMAP
≥98% (HPLC)
Synonym(s):
(2-Pyridylmethyl)(2-hydroxyphenyl)amine, 2-N-(2-Pyridylmethyl)aminophenol, 2-[(2-Pyridinylmethyl)amino]-phenol; (2-Hydroxyphenyl)(2-pyridylmethyl)amine
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About This Item
Empirical Formula (Hill Notation):
C12H12N2O
CAS Number:
Molecular Weight:
200.24
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
InChI
1S/C12H12N2O/c15-12-7-2-1-6-11(12)14-9-10-5-3-4-8-13-10/h1-8,14-15H,9H2
SMILES string
OC1=CC=CC=C1NCC2=NC=CC=C2
InChI key
GXJRVWZNMZGWAQ-UHFFFAOYSA-N
assay
≥98% (HPLC)
form
powder
color
, white to dark brown
solubility
DMSO: 20 mg/mL, clear
storage temp.
2-8°C
Biochem/physiol Actions
2-PMAP is a brain penetrant inhibitor of amyloid precursor protein (APP) production.
2-PMAP is a brain penetrant inhibitor of amyloid precursor protein (APP) production. 2-PMAP lowers levels of the amyloid precursor protein (APP) in CHO APP751SW cells. Also it reduces brain level of APP in mice model. 2-PMAP exhibits no cellular toxicity up to 100 μM.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Acute Tox. 4 Oral
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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