SML1230
XW4.4
≥98% (HPLC)
Synonym(s):
5-(2,6-Dichlorophenylsulfonamido)-N-(4-fluorobenzyl)-1H-pyrrole-2-carboxamide, 5-[[(2,6-Dichlorophenyl)sulfonyl]amino]-N-[(4-fluorophenyl)methyl]-1H-pyrrole-2-carboxamide
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About This Item
Empirical Formula (Hill Notation):
C18H14Cl2FN3O3S
CAS Number:
Molecular Weight:
442.29
UNSPSC Code:
12352200
Assay:
≥98% (HPLC)
Form:
powder
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 20 mg/mL, clear
storage temp.
2-8°C
Biochem/physiol Actions
XW4.4 can generate insulin-producing cells from rat mesenchymal stem cells. XW4.4 induced pancreatic differentiation of rat bone marrow derived mesenchymal stem cells into insulin-producing cells shown to release C-peptide and insulin in response to physiological or high glucose levels, which could lead to a possible treatment for Type 1 diabetes. Its mechanism of action is postulated to be through increasing expression of hepatocyte nuclear factor 3β (HNF3β), a member of the forkhead box transcription factor family that regulates expression of several genes in the pancreas during early embryogenesis.
XW4.4 generates insulin-producing cells from rat mesenchymal stem cells.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| SML1230-25MG | 04061832825434 |
| SML1230-5MG | 04061837107740 |
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