SML1384
BEC hydrochloride
≥98% (HPLC)
Synonym(s):
S-(2-Boronoethyl)-L-cysteine, S-(2-Boronoethyl)-L-cysteine hydrochloride
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
About This Item
Empirical Formula (Hill Notation):
C5H12BNO4S · xHCl
CAS Number:
Molecular Weight:
193.03 (free base basis)
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
Quality Level
assay
≥98% (HPLC)
form
powder
storage condition
desiccated
color
white to beige
solubility
H2O: 20 mg/mL, clear
storage temp.
−20°C
SMILES string
OB(O)CCSC[C@H](N)C(O)=O.C
InChI
1S/C5H12BNO4S.CH4/c7-4(5(8)9)3-12-2-1-6(10)11;/h4,10-11H,1-3,7H2,(H,8,9);1H4/t4-;/m0./s1
InChI key
IMYJQAMXIIYUIH-WCCKRBBISA-N
Biochem/physiol Actions
BEC is a boronic analog of L-arginine, and L-cysteine. It competitively inhibits both arginase I and II. BEC does not directly affect nitric oxide synthase.
BEC (S-(2-boronoethyl)-l-cysteine) is a potent and specific arginase inhibitor that restores flow-induced responses in arterioles from diabetic rats.
BEC (S-(2-boronoethyl)-l-cysteine) is a potent and specific arginase inhibitor.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Amino Acids in Human Nutrition and Health, 62-62 (2012)
Arginase inhibition restores arteriolar endothelial function in Dahl rats with salt-induced hypertension
Johnson FK, et al.
American Journal of Physiology. Lung Cellular and Molecular Physiology, 288(4), R1057-R1062 (2005)
Alessandra Romano et al.
Expert review of molecular diagnostics, 18(7), 675-683 (2018-05-01)
Despite improvement in overall response due to the introduction of the first-in-class proteasome inhibitor bortezomib (btz), multiple myeloma (MM) is still an incurable disease due to the immune-suppressive bone marrow (BM) environment. Thus, the authors aimed to identify the role
Global Trade Item Number
| SKU | GTIN |
|---|---|
| SML1384-25MG | 04061833225882 |
| SML1384-5MG | 04061833225899 |