SML1470
PACA
≥98% (HPLC)
Synonym(s):
3-(3,4-Dihydroxyphenyl)-N-2-propyn-1-yl-2-propenamide
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About This Item
Empirical Formula (Hill Notation):
C12H11NO3
CAS Number:
Molecular Weight:
217.22
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
Assay
≥98% (HPLC)
form
powder
color
white to light brown
solubility
DMSO: 25 mg/mL, clear
storage temp.
2-8°C
SMILES string
OC1=CC=C(/C=C/C(NCC#C)=O)C=C1O
InChI
1S/C12H11NO3/c1-2-7-13-12(16)6-4-9-3-5-10(14)11(15)8-9/h1,3-6,8,14-15H,7H2,(H,13,16)/b6-4+
InChI key
HLHSUNWAPXINQU-GQCTYLIASA-N
Biochem/physiol Actions
Nerve growth factor potentiator, activator of Nrf2/HO-1
PACA is a potentiator of NGF-induced neurite outgrowth that attenuates 6-hydroxydopamine (6-OHDA) neurotoxicity in dopaminergic PC12 cells. PACA induced the nuclear translocation of transcription factor Nrf2 and the expression of antioxidant heme oxygenase-1 (HO-1).
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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