Skip to Content
Merck
CN

Key Documents

View All Documentation

SML1487

ABT-089 dihydrochloride

≥98% (HPLC)

Synonym(s):

2-methyl-3-(2-(S)-pyrrolidinylmethoxy)pyridine dihydrochloride, Pozanicline dihydrochloride

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):
C11H16N2O · 2HCl
CAS Number:
161416-61-1
Molecular Weight:
265.18
UNSPSC Code:
12352200
PubChem Substance ID:
329825916
NACRES:
NA.77
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

assay

≥98% (HPLC)

form

powder

optical activity

[α]/D +20 to +30°, c = 1 in methanol

color

white to beige

solubility

H2O: 20 mg/mL, clear

storage temp.

2-8°C

SMILES string

CC1=C(OC[C@@H]2CCCN2)C=CC=N1.[H]Cl.[H]Cl

InChI

1S/C11H16N2O.2ClH/c1-9-11(5-3-6-12-9)14-8-10-4-2-7-13-10;;/h3,5-6,10,13H,2,4,7-8H2,1H3;2*1H/t10-;;/m0../s1

InChI key

UGVSESCRKJTJAK-XRIOVQLTSA-N

Biochem/physiol Actions

ABT-089 (Pozanicline) is a subtype-selective neuronal nicotinic receptor partial agonist binding primarily to the α4β2 and also α6β2 subtypes. It has been investigated for alleviating symptoms of nicotine withdrawal including cognitive deficits and anxiety.
ABT-089 is a subtype-selective neuronal nicotinic receptor partial agonist binding primarily to the α4β2 and also α6β2 subtypes.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
115M4605V

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library