SML1537
Cantharidin Ready Made Solution
0.1 mg/mL in DMSO
Synonym(s):
3a,7a-Dimethylhexahydro-4,7-epoxyisobenzofuran-1,3-dione, 7a-Dimethylhexahydro-3a,4,7-epoxyisobenzofuran, Cantharidine, Hexahydro-3a,7a-dimethyl-4,7-epoxyisobenzofuran-1,3-dione
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About This Item
Empirical Formula (Hill Notation):
C10H12O4
CAS Number:
Molecular Weight:
196.20
UNSPSC Code:
12352200
EC Number:
200-664-3
NACRES:
NA.77
Form:
solution
biological source
insect
Quality Segment
form
solution
concentration
0.1 mg/mL in DMSO
shipped in
ambient
storage temp.
2-8°C
SMILES string
O1[C@@H]2[C@]3([C@@]([C@H]1CC2)(C(=O)OC3=O)C)C
InChI
1S/C10H12O4/c1-9-5-3-4-6(13-5)10(9,2)8(12)14-7(9)11/h5-6H,3-4H2,1-2H3/t5-,6+,9+,10-
InChI key
DHZBEENLJMYSHQ-XCVPVQRUSA-N
Biochem/physiol Actions
Cantharidin inhibits protein phosphatase 2A.
It is a component of mylabris, a traditional Chinese medicine. Cantharidin exhibits anti-tumor activity. In addition, cantharidin can work against multidrug-resistant cells. In the epidermis, it causes release of neutral serine proteases, leading to degeneration of the desmosmal plaque. This results in acantholysis and intraepidermal blistering as well as skin lysis. PP2A is involved in the cell cycle, cell death, growth and cell-fate determination.
Other Notes
Stable for at least two years at 2-8° C.
Storage Class
10 - Combustible liquids
wgk
WGK 1
flash_point_f
188.6 °F
flash_point_c
87 °C
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