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Merck
CN

SML1632

Ceftezole Sodium

≥90% (HPLC)

Synonym(s):

(6R,7R)-8-oxo-7-{[2-(tetrazol-1-yl)acetyl]amino}-3-(1,3,4-thiadiazol-2-ylsulfanylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid sodium salt, Alomen, Celoslin, Falomesin

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About This Item

Empirical Formula (Hill Notation):
C13H11N8O4S3 · Na
CAS Number:
41136-22-5
Molecular Weight:
462.46
UNSPSC Code:
12352200
PubChem Substance ID:
329825976
NACRES:
NA.77

Key Documents

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SMILES string

O=C1[C@@H](NC(CN2N=NN=C2)=O)[C@]3([H])N1C(C([O-])=O)=C(CSC4=NN=CS4)CC3.[Na+]

InChI

1S/C13H12N8O4S3.Na/c22-7(1-20-4-14-18-19-20)16-8-10(23)21-9(12(24)25)6(2-26-11(8)21)3-27-13-17-15-5-28-13;/h4-5,8,11H,1-3H2,(H,16,22)(H,24,25);/q;+1/p-1/t8-,11-;/m1./s1

InChI key

UGUMHWUOXWFPFH-JHQAJZDGSA-M

biological source

synthetic

assay

≥90% (HPLC)

form

powder

solubility

H2O: soluble 200 mg/L

shipped in

ambient

storage temp.

−20°C

Biochem/physiol Actions

Ceftezole is a first generation cephalosporin with antibacterial activity.
Ceftezole is a first generation cephalosporin with antibacterial activity. Ceftezole binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity causing bacterial cell lysis.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H315,H319

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
037M4809V

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