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SML1811

BIQ

≥98% (HPLC)

Synonym(s):

FG 2216, FG-2216, IOX 3, N-[(1-Chloro-4-hydroxy-3-isoquinolinyl)carbonyl]glycine, YM 311, [[(1-Chloro-4-hydroxyisoquinolin-3-yl)carbonyl]amino]acetic acid

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About This Item

Empirical Formula (Hill Notation):
C12H9ClN2O4
CAS Number:
223387-75-5
Molecular Weight:
280.66
NACRES:
NA.77
PubChem Substance ID:
329826079
UNSPSC Code:
12352200
MDL number:
MFCD23136998
Assay:
≥98% (HPLC)
Form:
powder
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Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 10 mg/mL, clear

storage temp.

−20°C

SMILES string

OC1=C(C(NCC(O)=O)=O)N=C(Cl)C2=CC=CC=C21

InChI

1S/C12H9ClN2O4/c13-11-7-4-2-1-3-6(7)10(18)9(15-11)12(19)14-5-8(16)17/h1-4,18H,5H2,(H,14,19)(H,16,17)

InChI key

OUQVKRKGTAUJQA-UHFFFAOYSA-N

Biochem/physiol Actions

BIQ (FG-2216) is an orally available and potent inhibitor of prolyl-hydroxylase (PHD).
BIQ (FG-2216) is an orally available and potent inhibitor of prolyl-hydroxylase (PHD). BIQ induces significant and reversible plasma erythropoietin (EPO) levels in vitro and in hemodialysis patients.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Codes

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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