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Merck
CN

SML1856

8-Aminoguanine

≥95% (HPLC)

Synonym(s):

2,8-Diamino-1,9-dihydro-6H-purin-6-one; 2,8-Diamino-hypoxanthine, NSC 23170

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About This Item

Empirical Formula (Hill Notation):
C5H6N6O
CAS Number:
Molecular Weight:
166.14
NACRES:
NA.77
UNSPSC Code:
12352200
Assay:
≥95% (HPLC)
Form:
powder
Storage condition:
desiccated
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Quality Segment

assay

≥95% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

0.1 M NaOH: 2 mg/mL, clear (warmed)

storage temp.

2-8°C

SMILES string

O=C1C2=C(N=C(N)N2)NC(N)=N1

InChI

1S/C5H6N6O/c6-4-8-1-2(9-4)10-5(7)11-3(1)12/h(H6,6,7,8,9,10,11,12)

InChI key

WYDKPTZGVLTYPG-UHFFFAOYSA-N

Biochem/physiol Actions

8-Aminoguanine, a guanine derivative, is an orally available and highly efficacious potassium-sparing diuretic/natriuretic that increased sodium excretion by 17.2-fold and decrease potassium excretion by 71.0%. 8-Aminoguanine increases glucose excretion by 12.1-fold. Also, 8-Aminoguanine suppressed deoxycorticosterone/salt-induced hypertension.
8-Aminoguanine, a guanine derivative, is an orally available and highly efficacious potassium-sparing diuretic/natriuretic.


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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