SML2462
HZ-166
≥98% (HPLC)
Synonym(s):
8-Ethynyl-6-(2-pyridinyl)-4H-Imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid ethyl ester
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About This Item
Empirical Formula (Hill Notation):
C21H16N4O2
CAS Number:
Molecular Weight:
356.38
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
SMILES string
C#CC1=CC=C2C(C(C3=NC=CC=C3)=NCC4=C(C(OCC)=O)N=CN42)=C1
InChI key
ZSEDMNMFODMQRD-UHFFFAOYSA-N
Biochem/physiol Actions
HZ-166 is a potent, non-sedative GABAA receptor subtype-selective benzodiazepine site agonist exhibits preference toward α2- and α3-GABAARs. HZ-166 exhibits antihyperalgesic properties in mice models of neuropathic and inflammatory pain, without sedation and motor impairment.
potent, non-sedative GABAA receptor subtype-selective benzodiazepine site agonist exhibits preference toward α2- and α3-GABAARs
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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