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About This Item
Empirical Formula (Hill Notation):
C22H28N2O2
CAS Number:
Molecular Weight:
352.47
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to yellow-brown
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
SMILES string
N(C3CCCCC3)c1c(cc(cc1)C(=O)OCC)NCc2ccccc2
InChI key
VHQAJFNLPQULSV-UHFFFAOYSA-N
Biochem/physiol Actions
SRS11-92 is a cell penetrant and potent inhibitor of ferroptosis that attenuates the cell death associated with frataxin knockdown in healthy human fibroblasts. SRS11-92 protects against cell death in in a brain slice model of Huntington′s disease, an oligodendrocyte model of periventricular leukomalacia, and in isolated kidney proximal tubules model of kidney disfunction.
cell penetrant and potent inhibitor of ferroptosis that attenuates the cell death associated with frataxin knockdown in healthy human fibroblasts
Storage Class
11 - Combustible Solids
wgk
WGK 3
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