SML2808
Sparsentan
≥98% (HPLC), Angiotensin II receptor antagonist, powder
Synonym(s):
2-[4-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-2-(ethoxymethyl)phenyl]-N-(4,5-dimethyl-1,2-oxazol-3-yl)benzenesulfonamide, 4′-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-N-(4,5-dimethyl-3-isoxazolyl)-2′-(ethoxymethyl)[1,1′-biphenyl]-2-sulfonamide, BMS-346567, BMS346567, RE-021
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About This Item
Empirical Formula (Hill Notation):
C32H40N4O5S
CAS Number:
Molecular Weight:
592.75
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Product Name
Sparsentan, ≥98% (HPLC)
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
SMILES string
[S](=O)(=O)(Nc5n[o]c(c5C)C)c1c(cccc1)c2c(cc(cc2)CN3C(=O)C4(NC3=CCCC)CCCC4)COCC
InChI key
OIBXMWCQTPVHKR-UHFFFAOYSA-N
Biochem/physiol Actions
Sparsentan (BMS346567) is an orally available and highly potent dual antagonist of angiotensin II AT1 receptor and endothelin A ETA receptor. It is an analog of BMS-248360 that is orally available in rats and higher species.
orally available dual angiotensin II and endothelin A receptor antagonist
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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